APIs

PCI-32765

Name PCI-32765 Synonyms 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one Molecular Structure Molecular Formula C25H24N6O2 Molecular Weight 440.50 CAS Registry Number 936563-96-1

APIs

Crizotinib

Name Crizotinib Synonyms PF-02341066; 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine; PF 2341066 Molecular Structure Molecular Formula C21H22Cl2FN5O Molecular Weight 450.34 CAS Registry Number 877399-52-5

APIs

Brigatinib

Name Brigatinib Synonyms 5-Chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4-pyrimidinediamine; AP 26113 Molecular Structure Molecular Formula C29H39ClN7O2P Molecular Weight 584.09 CAS Registry Number 1197953-54-0

APIs

Lenvatinib mesylate

Name Lenvatinib mesylate Synonyms 4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide monomethanesulfonate; E 7080 mesylate Molecular Structure Molecular Formula C21H19ClN4O4.CH4O3S Molecular Weight 522.96 CAS Registry Number 857890-39-2

APIs

Voxilaprevir

Name Voxilaprevir Synonyms (1R,2R)-N-[[[(1R,2R)-2-[5,5-difluoro-5-(3-hydroxy-6-methoxy-2-quinoxalinyl)pentyl]cyclopropyl]oxy]carbonyl]-3-methyl-L-valyl-(3S,4R)-3-Ethyl-4-hydroxy-L-prolyl-1-amino-2-(difluoromethyl)-N-[(1-methylcyclopropyl)sulfonyl]cyclopropanecarboxamide cyclic (1→2)-ether Molecular Structure Molecular Formula C40H52F4N6O9S Molecular Weight 868.93 CAS Registry Number 1535212-07-7

APIs

Poziotinib

Name 1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one Molecular Structure Molecular Formula C23H21Cl2FN4O3 Molecular Weight 491.34 CAS Registry Number 1092364-38-9

APIs

Sorafenib tosylate

Name Sorafenib tosylate Molecular Structure Molecular Formula C21H16ClF3N4O3.C7H8SO3 Molecular Weight 637.03 CAS Registry Number 475207-59-1

APIs

Afatinib

Name Afatinib Synonyms BIBW 2992; Tovok; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide Molecular Structure Molecular Formula C24H25ClFN5O3 Molecular Weight 485.94 CAS Registry Number 850140-72-6

APIs

LDK 378

Name LDK 378 Synonyms 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine Molecular Structure Molecular Formula C28H36ClN5O3S Molecular Weight 558.14 CAS Registry Number 1032900-25-6